<b>Endocrine Disruptors and Hypothalamic Sexual Differentiation<b/>
نویسندگان
چکیده
منابع مشابه
Sexual behavior reduces hypothalamic androgen receptor immunoreactivity.
Male sexual behavior is regulated by limbic areas like the medial preoptic nucleus (MPN), the bed nucleus of the stria terminalis (BST), the nucleus accumbens (nAcc) and the ventromedial hypothalamic nucleus (VMN). Neurons in these brain areas are rich in androgen receptors (AR) and express FOS-immunoreactivity in response to mating. In many species sexual satiation, a state of sexual behavior ...
متن کامل[Impact of endocrine disruptors on the reproductive function and sexual response of men and women].
Os disruptores endócrinos são substâncias químicas naturais ou sintéticas, também contidas em compostos fungicidas, pesticidas e inseticidas, que apresentam ação antiandrogênica e estrogênica. Alguns desses compostos podem manter suas propriedades químicas na natureza por longos anos contaminando o ar, as águas e o solo, sendo acumuladas nas plantas, nos animais e no homem. Muitos são, potencia...
متن کاملEndocrine Disruptors and Obesity
PURPOSE OF REVIEW The purpose of this review was to summarise current evidence that some environmental chemicals may be able to interfere in the endocrine regulation of energy metabolism and adipose tissue structure. RECENT FINDINGS Recent findings demonstrate that such endocrine-disrupting chemicals, termed "obesogens", can promote adipogenesis and cause weight gain. This includes compounds ...
متن کاملOur stolen figures: The interface of sexual differentiation, endocrine disruptors, maternal programming, and energy balance
This article is part of a Special Issue "Energy Balance". The prevalence of adult obesity has risen markedly in the last quarter of the 20th century and has not been reversed in this century. Less well known is the fact that obesity prevalence has risen in domestic, laboratory, and feral animals, suggesting that all of these species have been exposed to obesogenic factors present in the environ...
متن کاملVENTROMEDIAL HYPOTHALAMIC NUCLEI AND FEEDING BEHAVIOR
The role of the ventromedial nuclei of the hypothalamus (VMN) in food behavior was studied in adult male rats, allocated in 3 groups: control, sham and lesioned. Electrolytic lesions were induced stereotaxically (1.2 mA, 15 sec). Results revealed a significant decrease (p<O.05) in body weight (BW) and food intake (FI) in the order of lesioned <sham <control during the fIrst week. However, ...
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ژورنال
عنوان ژورنال: Annual Review of Biomedical Sciences
سال: 2006
ISSN: 1806-8774,1517-3011
DOI: 10.5016/1806-8774.2003v5p87